![]() Therefore, it seems important to measure the amount of nicotine in different kinds of cigarettes which is generally used by the people in this country. 10- 15 There are many brands of cigarette (domestic and imported) available in Iranian market. People who smoke have more chronic illnesses, including emphysema and bronchitis, cardiovascular disease, cancer, bronchopulmonary disease, etc. Major symptoms of nicotine poisoning are sweating, vomiting, mental confusion, diminished pulse rate and breathing difficulty. It is colorless, highly volatile alkaloid. It is an alkaloid present in the leaves of Nicotiana tabacom. Nicotine is the major active molecule in cigarette smoke. 3- 7 It has been reported that to date, more than 3000 chemicals have been isolated from tobacco which more than 1000 of these chemical constituents present in unburnt. However the world cigarette production has increased about four times during the last 50 years. While the cigarette consumption has been increased in most of the developing countries, the past 25 years has been marked by a steady decline in cigarette consumption in some developed countries. ![]() 1, 2 There are approximately 1.25 billion smokers in the world representing about a third of the adult global population 800 million of these people live in developing countries. Tobacco use contributes in 10 global deaths and is the second major cause of mortality in the world. ![]() Using tobacco is one of the leading preventable causes of disease and premature death worldwide.
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